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Chebulagic acid
| Product Name | Chebulagic acid |
| Price: | $92 / 10mg |
| Catalog No.: | CN03897 |
| CAS No.: | 23094-71-5 |
| Molecular Formula: | C41H30O27 |
| Molecular Weight: | 954.7 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The fruits of Terminalia chebula. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OC(=O)C[C@@H]1C(=O)O[C@@H]2[C@H]3COC(=O)c4cc(O)c(c(c4c4c(C(=O)O[C@@H]2[C@@H](OC(=O)c2c5[C@H]1[C@H](O)C(=O)Oc5c(c(c2)O)O)[C@@H](O3)OC(=O)c1cc(O)c(c(c1)O)O)cc(O)c(c4O)O)O)O |
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| Description | Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis.target: COX-LOX [1]In vitro: Chebulagic acid can enhance the autophagy. Chebulagic acid exert anti-inflammatory and anti-infective effects. [1] [2] Chebulagic acid also show a protective effect against 1-methyl-4-phenylpyridinium (MPP+) - induce cytotoxicity which mimics the pathological symptom of Parkinson's disease. Chebulagic acid inhibit the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner. Furthermore, LPS-activated MAPK signaling is inhibited by CA treatment in the EA.hy926 cells. [3] |
| Density | 2.1±0.1 g/cm3 |
| Boiling Point | 1610.6±65.0 °C at 760 mmHg |
| Flash Point | 480.0±27.8 °C |
| Exact Mass | 954.097473 |
| PSA | 447.09000 |
| LogP | 2.25 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Storage condition | -20°C |